What is Ivermectin/Pyrantel?

Ivermectin/Pyrantel for dogs is a heartworm preventative that also controls roundworms and hookworms. Ivermectin/Pyrantel is a generic equivalent to Heartgard Plus. It has the same active ingredients and is the same strength. Ivermectin/Pyrantel is considered to be the #1 generic heartworm preventative recommended by veterinarians.
For: Dogs (6 weeks of age or older and no weight requirement)   Benefits: • Tasty flavored chewable tablets • Easy to administer • Small, easy-to-chew tablet for smaller or finicky dogs • Given once a month
How it works: Ivermectin/Pyrantel is an anthelmintic (dewormer). The ingredient pyrantel pamoate is used to treat and control roundworms and hookworms in dogs. Studies have indicated that certain dogs of the herding breeds are more sensitive to the effects of ivermectin administered at elevated dose levels due to the MDR1 gene. For a full list of dog breeds that may be affected, click here. Cautions: Can cause sensitivities in herding dog breeds. Side effects of Ivermectin/Pyrantel are rare, but may include lethargy, limpness, salivation, shaking, diarrhea, decreased appetite, licking lips, and belching. Don't give your pet Ivermectin/Pyrantel if already giving a different heartworm medication. The safe use of this drug has not been evaluated in pregnant or lactating bitches.
More Information:

Brand Name Iverhart Plus (Virbac), Tri-Heart Plus (Intervet)

Generic Name Ivermectin/Pyrantel

What is the most important information I should know about Ivermectin/Pyrantel: Ivermectin/Pyrantel is a prescription medication available as flavored chewable tablets. The usual dose of Ivermectin/Pyrantel in dogs up to 25 pounds is 68mcg/57mg (Blue box), for dogs 26-50 pounds is 136mcg/114mg (Green box) and for dogs 51-100 lbs 272mcg/227mg (Brown box). Dogs over 100 lbs are given a combination of tablets. What is Ivermectin/Pyrantel: Ivermectin/Pyrantel is given once a month for the prevention of heartworm disease in dogs. Ivermectin/Pyrantel also protects against hookworms and roundworms in dogs. It is recommended by the American Heartworm Society that heartworm prevention be given year-round. Ivermectin/Pyrantel may also be used for purposes other than those listed in this guide. What should I discuss with my veterinarian before giving Ivermectin/Pyrantel to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to the medication. How should this medication be given: Give Ivermectin/Pyrantel exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Use with caution, Collies and other herding dog breeds have been known to have adverse reactions to invermectin administered at elevated dose levels. Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Ivermectin/Pyrantel for 6 months or less, start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Ivermectin/Pyrantel at room temperature. Do not remove the tablet from its wrapper until ready to give to your pet. Keep this medication away from children and pets. The safe use of this drug has not been evaluated in pregnant or lactating bitches.  What happens if I miss giving a dose: Give the missed dose as soon as you remember. Do not give a double dose of the medication. What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include vomiting, diarrhea, and lack of coordination in dogs. What should I avoid while giving Ivermectin/Pyrantel to my pet: Because humans can contract hookworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the household and to not feed your pet rodents. To prevent reinfection, daily cleanup of stools is recommended. What are the possible side effects of Ivermectin/Pyrantel: Side effects of Ivermectin/Pyrantel are rare at the recommended heartworm prevention dose. Higher doses in dogs may cause tremors, dilated pupils, loss of body weight, or death. What other drugs will affect Ivermectin/Pyrantel: Do not give Ivermectin/Pyrantel if your pet is already being given another heartworm medication. Where can I get more information: Your pharmacist has additional information about Ivermectin/Pyrantel written for health professionals that you may read.